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  AIM: High Rates of Adverse Drug Events in a Highly Computerized Hospital
Journal of Free and Open Source Medical Computing Posted by Ignacio Valdes, MD, MS on Monday May 30, @10:08AM
from the dept.
Z The Archives of Internal Medicine have a report about high rates of adverse drug effects in a hospital that is highly computerized: '...Among 937 hospital admissions, 483 clinically significant inpatient [Adverse Drug Effects] ADEs were identified, accounting for 52 ADEs per 100 admissions and an incidence density of 70 ADEs per 1000 patient-days. One quarter of the hospitalizations had at least 1 ADE. Of all ADEs, 9% resulted in serious harm, 22% in additional monitoring and interventions, 32% in interventions alone, and 11% in monitoring alone; 27% should have resulted in additional interventions or monitoring. Medication errors contributed to 27% of these ADEs. Errors associated with ADEs occurred in the following stages: 61% ordering, 25% monitoring, 13% administration, 1% dispensing, and 0% transcription. The medical record reflected recognition of 76% of the ADEs. Conclusions High rates of ADEs may continue to occur after implementation of CPOE and related computerized medication systems that lack decision support for drug selection, dosing, and monitoring...'


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